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VPS37A Rabbit pAb

Anti-VPS37A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218017

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218017
Product Name:   Anti-VPS37A Rabbit Polyclonal Antibody
Synonyms:   HCRP1; PQBP2; SPG53
UNIPROT ID:   Q8NEZ2 (Gene Accession – BC022363 )
Background:    This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein comple,x required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
Immunogen:    Fusion protein of human VPS37A
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218017(VPS37A Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218017(Anti-VPS37A Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 218017(Anti-VPS37A Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D223556(Anti-VPS37A Antibody) at dilution 1/30.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human bladder carcinoma and fetal liver tissue;
Primary antibody: 218017(VPS37A Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 15 seconds
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