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VTI1A Rabbit pAb

Anti-VTI1A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218297

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218297
Product Name:   Anti-VTI1A Rabbit Polyclonal Antibody
Synonyms:   MMDS3; MVti1; VTI1RP2; Vti1-rp2
UNIPROT ID:   Q96AJ9 (Gene Accession – BC017052 )
Background:    The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
Immunogen:    Full length fusion protein
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 218297(VTI1A Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 218297(Anti-VTI1A Antibody) at dilution 1/35.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: HEPG2, Hela, Jurkat, 231 and HUVEC cell lysates;
Primary antibody: 218297(VTI1A Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 seconds
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