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WNK3 Rabbit pAb

Anti-WNK3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221133

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221133
Product Name:   Anti-WNK3 Rabbit Polyclonal Antibody
Synonyms:   PRKWNK3
UNIPROT ID:   Q9BYP7 (Gene Accession – NP_065973 )
Background:    This gene encodes a protein belonging to the ‘with no lysine’ family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Immunogen:    Synthetic peptide of human WNK3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221133(WNK3 Antibody) at a dilution of 1/30(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221133(Anti-WNK3 Antibody) at dilution 1/30.
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