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WNK4 Rabbit pAb

Anti-WNK4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221136

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221136
Product Name:   Anti-WNK4 Rabbit Polyclonal Antibody
Synonyms:   PHA2B; PRKWNK4
UNIPROT ID:   Q96J92 (Gene Accession – NP_115763 )
Background:    This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.
Immunogen:    Synthetic peptide of human WNK4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221136(WNK4 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221136(Anti-WNK4 Antibody) at dilution 1/45.
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