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Wnt1 Rabbit pAb

Anti-Wnt1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225100

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225100
Product Name:   Anti-Wnt1 Rabbit pAb
Synonyms:   WNT1; INT1; Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog
UNIPROT ID:   P04628
Background:    WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
Immunogen:    The antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350
Applications:    WB,IHC-F,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 41 kDa; Observed MW: 45 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Wnt1 in HT-29 lysates using Wnt1 antibody.

Western blot analysis of Wnt1 in various lysates using Wnt1 antibody.
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