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WNT6 Rabbit pAb

Anti-WNT6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221139

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221139
Product Name:   Anti-WNT6 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q9Y6F9 (Gene Accession – NP_006513 )
Background:    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
Immunogen:    Synthetic peptide of human WNT6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Neuroscience, Signal Transduction, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221139(WNT6 Antibody) at a dilution of 1/35(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221139(Anti-WNT6 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 221139(Anti-WNT6 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D262607(Anti-WNT6 Antibody) at dilution 1/35.
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