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WRAP53 Rabbit pAb

Anti-WRAP53 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218029

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218029
Product Name:   Anti-WRAP53 Rabbit Polyclonal Antibody
Synonyms:   DKCB3; TCAB1; WDR79
UNIPROT ID:   Q9BUR4 (Gene Accession – BC002336 )
Background:    This gene encodes an essential component of the telomerase holoenzyme comple,x a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs.
Immunogen:    Fusion protein of human WRAP53
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 218029(WRAP53 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 218029(Anti-WRAP53 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HT-29, Hela and A431 cell lysates;
Primary antibody: 218029(WRAP53 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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