NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S221149 | ||
Product Name: Anti-XKR4 Rabbit Polyclonal Antibody | ||
Synonyms: XRG4 | ||
UNIPROT ID: Q5GH76 (Gene Accession – NP_443130 ) | ||
Background: XKR4 (XK-related protein 4) is a 650 amino acid multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR4 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Single nucleotide polymorphisms (SNPs) of the XKR4 gene are associated with iloperidone efficacy, a antipsychotic drug that is used to treat schizophrenic patients. | ||
Immunogen: Synthetic peptide of human XKR4 | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: 50-200; ELISA: 5000-10000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human, Mouse, Rat | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Cell Biology | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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