NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S211781 | ||
Product Name: Anti-XKR6 Rabbit Polyclonal Antibody | ||
Synonyms: XRG6; C8orf5; C8orf7; C8orf21 | ||
UNIPROT ID: Q5GH73 (Gene Accession – BC024146 ) | ||
Background: XK is a 444 amino acid protein that spans the membrane 10 times and carries the ubiquitous antigen, K,x which determines blood type. The XK (X-linked Kx blood group)-related gene family are homologs of XK. XKR6 (XK-related protein 6) is a 641 amino acid multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR6 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. There are two isoforms of XKR6 that are produced as a result of alternative splicing events. | ||
Immunogen: Fusion protein of human XKR6 | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: 150-300; ELISA: 5000-10000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human, Mouse, Rat | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Cell Biology | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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