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XRCC6 Rabbit pAb

Anti-XRCC6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216608

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216608
Product Name:   Anti-XRCC6 Rabbit Polyclonal Antibody
Synonyms:   ML8, KU70, TLAA, CTC75, CTCBF, G22P1
UNIPROT ID:   P12956 (Gene Accession – BC008343 )
Background:    The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Immunogen:    Fusion protein of human XRCC6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216608(XRCC6 Antibody) at a dilution of 1/10(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216608(Anti-XRCC6 Antibody) at dilution 1/10.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 216608(Anti-XRCC6 Antibody) at a dilution of 1/10.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D220909(Anti-XRCC6 Antibody) at dilution 1/10.
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