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YPEL4 Rabbit pAb

Anti-YPEL4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221533

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221533
Product Name:   Anti-YPEL4 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q96NS1 (Gene Accession – NP_659445 )
Background:    YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP). It has been suggested that MVP can inhibit YPEL4’s ability to activate Elk-1 in the MAPK signaling pathway.
Immunogen:    Synthetic peptide of human YPEL4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221533(YPEL4 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221533(Anti-YPEL4 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 221533(Anti-YPEL4 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D263169(Anti-YPEL4 Antibody) at dilution 1/25.
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