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ZFP36 Rabbit pAb

Anti-ZFP36 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218227

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218227
Product Name:   Anti-ZFP36 Rabbit Polyclonal Antibody
Synonyms:   TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
UNIPROT ID:   P26651 (Gene Accession – BC009693 )
Background:    mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).
Immunogen:    Fusion protein of human ZFP36
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Neuroscience, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218227(ZFP36 Antibody) at a dilution of 1/40(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218227(Anti-ZFP36 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 218227(Anti-ZFP36 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D223985(Anti-ZFP36 Antibody) at dilution 1/40.
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