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ZGPAT ? Rabbit pAb

Anti-ZGPAT ? Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213324

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213324
Product Name:   Anti-ZGPAT Rabbit Polyclonal Antibody
Synonyms:   ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847; RP4-583P15.3
UNIPROT ID:   Q8N5A5 (Gene Accession – NP_115916 )
Background:    ZGPAT (Zinc finger CCCH-type with G patch domain-containing protein), also known as zinc finger CCCH domain-containing protein 9 (ZC3HDC9) and G patch domain-containing protein 6 (GPATC6), is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.
Immunogen:    Synthetic peptide of human ZGPAT
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 213324(ZGPAT Antibody) at a dilution of 1/60(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 213324(Anti-ZGPAT Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213324(Anti-ZGPAT Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D156031(Anti-ZGPAT Antibody) at dilution 1/60.
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