NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S214932 | ||
Product Name: Anti-ZNF146 Rabbit Polyclonal Antibody | ||
Synonyms: OZF | ||
UNIPROT ID: Q15072 (Gene Accession – NP_009076 ) | ||
Background: ZNF146 (zinc finger protein 146), also known as OZF (only zinc finger protein), is a 292 amino acid nuclear protein that binds DNA and belongs to the Krppel C2H2-type zinc-finger protein family. ZNF146 interacts with UBC9 (ubiquitin carrier protein 9) and RAP1 (repressor/activator protein 1 homolog), and is highly expressed in multiple pancreatic and colorectal cancers. Lower levels of expression have been observed in kidney, lung, placenta and brain. | ||
Immunogen: Synthetic peptide of human ZNF146 | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human, Mouse | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Epigenetics and Nuclear Signaling, Cancer | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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