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ZNHIT1 Rabbit pAb

Anti-ZNHIT1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218052

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218052
Product Name:   Anti-ZNHIT1 Rabbit Polyclonal Antibody
Synonyms:   CG1I; ZNFN4A1
UNIPROT ID:   O43257 (Gene Accession – BC017333 )
Background:    ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
Immunogen:    Full length fusion protein
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218052(ZNHIT1 Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218052(Anti-ZNHIT1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 218052(Anti-ZNHIT1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D223618(Anti-ZNHIT1 Antibody) at dilution 1/40.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: 293T cell lysate ;
Primary antibody: 218052(ZNHIT1 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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