Subtotal:
$347.00
$445.00
| Cat.#: 28351 | ||
| Product Name: Anti-B7-H3(DM53) Rabbit Monoclonal Antibody | ||
| Synonyms: B7-H3; CD276; B7 homolog 3; B7H3 | ||
| Description: Anti-B7-H3 antibody(DM53) Rabbit Monoclonal Antibody | ||
| Background: The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | ||
| Applications: ELISA; Flow Cyt | ||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
| Host Species: Rabbit | ||
| Isotype: Rabbit IgG | ||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||
| Species Reactivity: Human B7-H3 | ||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
|
