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Human CB2 Full Length Protein

Human CB2 Full Length Protein-Synthetic Nanodisc


Cat.#:  11119

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11119
Product Name:   Human CB2 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CB-2; CNR2; CX5
Target:    CB2
UNIPROT ID:    P34972
Description:    Human CB2 full length protein-synthetic nanodisc
Background:     The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Species/Host:    HEK293
Molecular Weight:    The human full length CB2 protein has a MW of 39.7 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CB2-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CB2-Nanodisc is 1.557ng/ml.

Figure2. Human CB2-Nanodisc, Flag Tag on SDS-PAGE