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Human CCR6 Full Length Protein

Human CCR6 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11040

   Size:   50 μg

In Stock

            Product Description          
Cat.#:     11040
Product Name:   Human CCR6 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
Target:    CCR6
UNIPROT ID:    P51684
Description:    Human CCR6 full length protein-synthetic nanodisc
Background:     The protein is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Species/Host:    HEK293
Molecular Weight:    The human full length CCR6 protein has a MW of 42.5 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CCR6-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CCR6-Nanodisc is 2.691ng/ml.

Figure2. Human CCR6-Nanodisc, Flag Tag on SDS-PAGE
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