Email: info@neweastbio.com   |  Call: 6109452007

CD43 (DM211) Rabbit mAb

Anti-CD43 (DM211) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28554

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28554
Product Name:   Anti-CD43(DM211) Rabbit Monoclonal Antibody
Synonyms:   CD43; GALGP; GPL115; LSN
Description:    Anti-CD43 antibody(DM211) Rabbit Monoclonal Antibody
Background:    This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells; and is found on the surface of thymocytes; T lymphocytes; monocytes; granulocytes; and some B lymphocytes. It contains a mucin-like extracellular domain; a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues; allowing extensive O-glycosylation; and has one potential N-glycosylation site; while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells; proteolytic cleavage of the extracellular domain occurs in some cell types; releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq; Sep 2017]
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD43
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CD43 (DM211) on Expi293 cells transfected with human CD43 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
          Publications