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CD63 (DMC425) IgG1 Chimeric mAb

Anti-CD63 (DMC425) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28219

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28219
Product Name:   Anti-CD63(DMC425) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CD63 antigen;Granulophysin;LAMP-3;Limp1;Melanoma-associated antigen ME491;OMA81H;Ocular melanoma-associated antigen;Tetraspanin-30;Tspan-30
Description:    Anti-CD63 antibody(DMC425) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a member of the transmembrane 4 superfamily; also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development; activation; growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD63
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. CD63 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD63 (DMC425) on Expi293 cells transfected with human CD63 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).