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CXCL1 (DMC499) IgG1 Chimeric mAb

Anti-CXCL1 (DMC499) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28272

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28272
Product Name:   Anti-CXCL1(DMC499) IgG1 Chimeric Monoclonal Antibody
Synonyms:   FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Description:    Anti-CXCL1 antibody(DMC499) IgG1 Chimeric Monoclonal Antibody
Background:    This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor; CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq; Sep 2014]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CXCL1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CXCL1 (DMC499) on Expi293 cells transfected with human CXCL1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).