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DDR1 (DMC480) IgG1 Chimeric mAb

Anti-DDR1 (DMC480) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28256

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28256
Product Name:   Anti-DDR1(DMC480) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; MCK-10; HGK2; CD167a
Description:    Anti-DDR1 antibody(DMC480) IgG1 Chimeric Monoclonal Antibody
Background:    Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth; differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain; and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells; particularly in the kidney; lung; gastrointestinal tract; and brain. In addition; it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq; Feb 2011]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human DDR1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-DDR1 (DMC480) on Expi293 cells transfected with human DDR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).