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TIGIT mAb (Etigilimab)

Anti-TIGIT? Monoclonal Antibody (EtigiliMonoclonal Antibody)?
5/5

$199.00

Cat.#:  28033

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28033
Product Name:   Anti-TIGIT (Etigilimab) Monoclonal Antibody
Synonyms:   TIGIT;SIG9;STM3
Description:    Anti-TIGIT (etigilimab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Humanized
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human TIGIT
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, His tagged protein 11309 can bind Anti-TIGIT Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, mFc tagged protein 11308 can bind Anti-TIGIT Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.

Figure 3. HEK293 cell line transfected with irrelevant protein  (B) and human TIGIT protein  (A) were surface stained with anti-TIGIT neutralizing antibody 1µg/ml (etigilimab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
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