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FOLR1 (DMC391) IgG1 Chimeric mAb

Anti-FOLR1 (DMC391) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28209

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28209
Product Name:   Anti-FOLR1(DMC391) IgG1 Chimeric Monoclonal Antibody
Synonyms:   FBP; FOLR; FRalpha
Description:    Anti-FOLR1 antibody(DMC391) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives; and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters; multiple transcription start sites; and alternative splicing; multiple transcript variants encoding the same protein have been found for this gene.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human FOLR1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. FOLR1 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-FOLR1 (DMC391) on Expi293 cells transfected with human FOLR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).