Subtotal:
$347.00
$445.00
| Cat.#: 28209 |
| Product Name: Anti-FOLR1(DMC391) IgG1 Chimeric Monoclonal Antibody |
| Synonyms: FBP; FOLR; FRalpha |
| Description: Anti-FOLR1 antibody(DMC391) IgG1 Chimeric Monoclonal Antibody |
| Background: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives; and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters; multiple transcription start sites; and alternative splicing; multiple transcript variants encoding the same protein have been found for this gene. |
| Applications: Flow Cyt |
| Recommended Dilutions: Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit:Human Fc chimeric IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human FOLR1 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. FOLR1 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-FOLR1 (DMC391) on Expi293 cells transfected with human FOLR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram). |
