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FZD10 (DMC487) IgG1 Chimeric mAb

Anti-FZD10 (DMC487) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28263

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28263
Product Name:   Anti-FZD10(DMC487) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CD350; FZ-10; Fz10; FzE7; hFz10
Description:    Anti-FZD10 antibody(DMC487) IgG1 Chimeric Monoclonal Antibody
Background:    This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis; expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq; Jul 2008]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human FZD10
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-FZD10 (DMC487) on Expi293 cells transfected with human FZD10 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).