$445.00
Cat.#: 28263 |
Product Name: Anti-FZD10(DMC487) IgG1 Chimeric Monoclonal Antibody |
Synonyms: CD350; FZ-10; Fz10; FzE7; hFz10 |
Description: Anti-FZD10 antibody(DMC487) IgG1 Chimeric Monoclonal Antibody |
Background: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis; expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq; Jul 2008] |
Applications: Flow Cyt |
Recommended Dilutions: Flow Cyt 1:100 |
Host Species: Rabbit |
Isotype: Rabbit:Human Fc chimeric IgG1 |
Purification: Purified from cell culture supernatant by affinity chromatography |
Species Reactivity: Human FZD10 |
Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
![]() Figure 1. Flow cytometry analysis with Anti-FZD10 (DMC487) on Expi293 cells transfected with human FZD10 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |