Subtotal:
$659.00
$445.00
| Cat.#: 28401 | ||||
| Product Name: Anti-GITR(DM80) Rabbit Monoclonal Antibody | ||||
| Synonyms: AITR; GITR; TNFRSF18; CD357 | ||||
| Description: Anti-GITR antibody(DM80) Rabbit Monoclonal Antibody | ||||
| Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. | ||||
| Applications: ELISA; Flow Cyt | ||||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||||
| Host Species: Rabbit | ||||
| Isotype: Rabbit IgG | ||||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||||
| Species Reactivity: Human GITR | ||||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||||
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