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HBEGF (DMC500) IgG1 Chimeric mAb

Anti-HBEGF (DMC500) IgG1 Chimeric Monoclonal Antibody
5/5

$445.00

Cat.#:  28273

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28273
Product Name:   Anti-HBEGF(DMC500) IgG1 Chimeric Monoclonal Antibody
Synonyms:   DTR; DTS; DTSF; HEGFL
Description:    Anti-HBEGF antibody(DMC500) IgG1 Chimeric Monoclonal Antibody
Background:    Growth factor that mediates its effects via EGFR; ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts; but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human HBEGF
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-HBEGF(DMC500) on Expi293 cells transfected with human HBEGF (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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