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$445.00
| Cat.#: 11195 | ||
| Product Name: Human ACE2 Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: ACE-2;CEH;CE2 | ||
| Target: ACE2 | ||
| UNIPROT ID: Q9BYF1 | ||
| Description: Recombinant human ACE2 protein with C-terminal mouse Fc tag | ||
| Background: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 109.7 kDa after removal of the signal peptide. | ||
| Molecular Characterization: ACE2(Gln18-Ser740) mFc(Pro99-Lys330) | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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