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Human ADAM8 Protein, His Tag

Recombinant human ADAM8 protein with C-terminal 6XHis tag


Cat.#:  11515

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11515
Product Name:   Human ADAM8 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Cell surface antigen MS2;D156a
Target:    ADAM8
UNIPROT ID:    P78325
Description:    Recombinant human ADAM8 protein with C-terminal 6xHis tag
Background:     This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 70.6 kDa after removal of the signal peptide. The apparent molecular mass of ADAM8-His is approximately 55-70 kDa and 70-100 kDa due to glycosylation.
Molecular Characterization:    ADAM8(Ile17-Pro655) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human  ADAM8 Protein, His Tag on SDS-PAGE under reducing condition.