Cat.#: 11663 |
Product Name: Human ADAM9 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: CORD9;MCMP;MDC9;Mltng |
Target: ADAM9 |
UNIPROT ID: Q13443 |
Description: Recombinant human ADAM9 Protein with C-terminal 6xHis tag |
Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 74.8 kDa after removal of the signal peptide. |
Molecular Characterization: ADAM9(Ala29-Asp697) 6×His Tag |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
 Figure 1. Human ADAM9 Protein, His Tag on SDS-PAGE under reducing (R) conditions. |  Figure 2. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human ADAM9 protein, His Tag (11663) can bind Anti-ADAM9 Neutralizing antibody 28071 in a linear range of 0.128-16 ng/mL. |
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