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Human BMP2 Protein, hFc Tag

Recombinant Human BMP2 Protein with C-terminal human Fc tag
5/5

$415.00

Cat.#:  11875

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11875
Product Name:   Human BMP2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   BDA2;BMP2A;SSFSC;SSFSC1
Target:    BMP2
UNIPROT ID:    P12643
Description:    Recombinant Human BMP2 Protein with C-terminal human Fc tag
Background:     This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide. The apparent molecular mass of BMP2-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    BMP2(Gln283-Arg396) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human BMP2 Protein, hFc Tag on SDS-PAGE under reducing condition.
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