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Human BRD4 Protein, hFc Tag

Recombinant human BRD4 protein with C-terminal human Fc tag


Cat.#:  11668

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11668
Product Name:   Human BRD4 Protein
Size :    10 µg, 50 µg and 100 µg
Target:    BRD4
UNIPROT ID:    O60885
Description:    Recombinant human BRD4 protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 178.4 kDa after removal of the signal peptide.
Molecular Characterization:    BRD4(Met1-Phe1362) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human BRD4 Protein, hFc Tag on SDS-PAGE under reducing condition.