Subtotal:
$239.00
$1,600.00
| Cat.#: 12227 | ||
| Product Name: Human CB1 Full Length Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: CANN6; CB-R; CNR1; CB1A; CB1K5; CB1R; CNR | ||
| Target: CB1 | ||
| UNIPROT ID: P21554 | ||
| Description: Human CB1 full length protein membrane nanoparticles (MNPs) | ||
| Background: The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The human full length CB1 Protein has a MW of 52.7 kDa | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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