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Human CB2 Protein, hFc Tag

Recombinant Human CB2 Protein with C-terminal human Fc tag


Cat.#:  11670

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11670
Product Name:   Human CB2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CB-2;CB2;CX5
Target:    CB2
UNIPROT ID:    P34972
Description:    Recombinant Human CB2 Protein with C-terminal human Fc tag
Background:     The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 33.9 kDa after removal of the signal peptide.The apparent molecular mass of CB2-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CB2(Met1-Lys33) (Asn93-Ala104) (Thr173-Asn188) (Ala270-Lys278) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CB2 Protein, hFc Tag on SDS-PAGE under reducing condition.