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Human CCL1 Protein

Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
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$525.00

Cat.#:  12032

   Size:   50 μg

In Stock

            Product Description          
Cat.#:     12032
Product Name:   Human CCL1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   C-C Motif Chemokine 1;Small-Inducible Cytokine A1;T Lymphocyte-Secreted Protein I-309;CCL1;SCYA1
Target:    CCL1
UNIPROT ID:    P22362
Description:    Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
Background:     Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
Species/Host:    E.coli
Molecular Weight:    8.62 KDa
Molecular Characterization:    Not available
Purity:    Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
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