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Human CCL11 Protein, hFc Tag

Recombinant Human CCL11 Protein with C-terminal human Fc tag
5/5

$389.00

Cat.#:  11971

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11971
Product Name:   Human CCL11 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   SCYA11
Target:    CCL11
UNIPROT ID:    P51671
Description:    Recombinant Human CCL11 Protein with C-terminal human Fc tag
Background:     This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 34.0 kDa after removal of the signal peptide. The apparent molecular mass of CCL11-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CCL11(Thr30-Pro97) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human CCL11 Protein, hFc Tag on SDS-PAGE under reducing condition.
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