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Human CD106 Protein, hFc Tag

Recombinant human CD106 Protein with C-terminal Human Fc tag


Cat.#:  11808

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11808
Product Name:   Human CD106 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   VCAM1;INCAM-100
Target:    CD106
UNIPROT ID:    P19320
Description:    Recombinant human CD106 Protein with C-terminal Human Fc tag
Background:     This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 100.4 kDa after removal of the signal peptide. The apparent molecular mass of CD106-hFc is approximately 100-130 kDa due to glycosylation.
Molecular Characterization:    CD106(Phe25-Glu698) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD106 Protein, hFc Tag on SDS-PAGE under reducing condition.