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Human CD11 Protein, hFc Tag

Recombinant human CD11 protein with C-terminal human Fc tag
5/5

$415.00

Cat.#:  11766

   Size:   100 μg

Under development

            Product Description          
Cat.#:     11766
Product Name:   Human CD11 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD11A;LFA-1;LFA1A
Target:    CD11
UNIPROT ID:    P20701
Description:    Recombinant human CD11 protein with C-terminal human Fc tag
Background:     ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 142.67 kDa after removal of the signal peptide.
Molecular Characterization:    CD11 (Pro26-Leu1090) hFc(Glu99-ALA330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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