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Human CD14(20-344) Protein, His Tag

Recombinant Human CD14(20-344) Protein with C-terminal 6XHis tag


Cat.#:  11888

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11888
Product Name:   Human CD14(20-344) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD14 Molecule;yeloid Cell-Specific Leucine-Rich Glycoprotein;D14 Antigen;onocyte Differentiation Antigen CD14
Target:    CD14
UNIPROT ID:    P08571
Description:    Recombinant Human CD14(20-344) Protein with C-terminal 6xHis tag
Background:     The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 35.9 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-344)-His is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CD14(Thr20-Met344) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human CD14(20-344) Protein, His Tag on SDS-PAGE under reducing condition.