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Human CD19 Protein, mFc Tag

Recombinant human CD19 protein with C-terminal mouse Fc tag


Cat.#:  11569

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11569
Product Name:   Human CD19 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   B4;CVID3;MGC12802
Target:    CD19
UNIPROT ID:    P15391
Description:    Recombinant human CD19 protein with C-terminal mouse Fc tag
Background:     Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 56.3 kDa after removal of the signal peptide. The apparent molecular mass of CD19-mFc is approximately 70-100 kDa due to glycosylation.
Molecular Characterization:    CD19(Pro20-Lys291) mFc(Pro99-Lys330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD19 Protein, mFc Tag on SDS-PAGE under reducing condition.