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Human CD3D Protein, His Tag

Recombinant human CD3D protein with C-terminal 6XHis tag
5/5

$415.00

Cat.#:  11586

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11586
Product Name:   Human CD3D Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   T-cell surface glycoprotein CD3 delta chain;-cell receptor T3 delta chain
Target:    CD3D
UNIPROT ID:    P04234
Description:    Recombinant human CD3D protein with C-terminal 6xHis tag
Background:     The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 10.4 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His is approximately 15-25 kDa due to glycosylation.
Molecular Characterization:    CD3D(Phe22-Ala105) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD3D Protein, His Tag on SDS-PAGE under reducing condition.
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