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Human CD63 Protein, hFc Tag

Recombinant human CD63 protein with C-terminal human Fc tag


Cat.#:  11531

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11531
Product Name:   Human CD63 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD63 antigen;ranulophysin;AMP-3;imp1;elanoma-associated antigen ME491;MA81H;cular melanoma-associated antigen;etraspanin-30;Tspan-30
Target:    CD63
UNIPROT ID:    P08962
Description:    Recombinant human CD63 protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide. The apparent molecular mass of CD63-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CD63(Ala103-Val203) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD63 Protein, hFc Tag on SDS-PAGE under reducing condition.