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Human CDH11(54-617) Protein, His Tag

Recombinant Human CDH11(54-617) Protein with C-terminal 6XHis tag


Cat.#:  11834

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11834
Product Name:   Human CDH11(54-617) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CAD11;CDHOB;ESWS;OB;OSF-4
Target:    CDH11
UNIPROT ID:    P55287
Description:    Recombinant Human CDH11(54-617) Protein with C-terminal 6xHis tag
Background:     This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 62.8 kDa after removal of the signal peptide. The apparent molecular mass of CDH11(54-617)-His is approximately 70-100 kDa due to glycosylation.
Molecular Characterization:    CDH11(54-617)(Gly54-Thr617) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CDH11(54-617) Protein, His Tag on SDS-PAGE under reducing condition.