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Human CLDN2 Protein, hFc Tag

Recombinant human CLDN2 protein with C-terminal human Fc tag


Cat.#:  11570

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11570
Product Name:   Human CLDN2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Claudin-2;SP82
Target:    CLDN2
UNIPROT ID:    P57739
Description:    Recombinant human CLDN2 protein with C-terminal human Fc tag
Background:     This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of CLDN2-hFc is approximately 25-35 kDa due to glycosylation.
Molecular Characterization:    CLDN2(Ser29-Gln78) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CLDN2 Protein, hFc Tag on SDS-PAGE under reducing condition.