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Human ECSCR Protein, hFc Tag

Recombinant Human ECSCR Protein with C-terminal human Fc tag


Cat.#:  11937

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11937
Product Name:   Human ECSCR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ARIA;ECSM2
Target:    ECSCR
Description:    Recombinant Human ECSCR Protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ECSCR-hFc is approximately 35-70 kDa due to glycosylation.
Molecular Characterization:    ECSCR(Gln25-Val122) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human ECSCR Protein, hFc Tag on SDS-PAGE under reducing condition.