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Human F2RL1 Protein, hFc Tag

Recombinant human F2RL1 protein with C-terminal human Fc tag


Cat.#:  11785

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11785
Product Name:   Human F2RL1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   GPR11;PAR2
Target:    F2RL1
UNIPROT ID:    P55085
Description:    Recombinant human F2RL1 protein with C-terminal human Fc tag
Background:     This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of F2RL1-hFc is approximately 33-53 kDa due to glycosylation.
Molecular Characterization:    F2RL1(Ser37-Gly71) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human F2RL1 Protein, hFc Tag on SDS-PAGE under reducing condition.