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Human FZD10 Protein, hFc Tag

Recombinant Human FZD10 with C-terminal human Fc tag


Cat.#:  11446

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11446
Product Name:   Human FZD10 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD350;FZ-10;Fz10;FzE7;hFz10
Target:    FZD10
Description:    Recombinant Human FZD10 with C-terminal human Fc tag
Background:     This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide. The apparent molecular mass of FZD10-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    FZD10(Ile21-Gly161) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FZD10 Protein, hFc Tag on SDS-PAGE under reducing condition.