Email:   |  Call: 6109452007

Human GITR Ligand Protein, His tag

Recombinant human GITR Ligand protein with C-terminal His tag


Cat.#:  11288

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11288
Product Name:   Human GITR Ligand Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TNFSF18;AITRL;TL6;hGITRL;GITR Ligand
Target:    GITR Ligand
Description:    Recombinant human GITR Ligand protein with C-terminal His tag
Background:     The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 15.3 kDa after removal of the signal peptide.
Molecular Characterization:    GITR Ligand(Gln50-Ser177) 6×His
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GITR Ligand Protein, His Tag on SDS-PAGE under reducing condition.

Figure 2.  Flow cytometry analysis with 1 µg/ml Human GITR Ligand Protein, His tag (11288) on Expi293 cells transfected with human GITR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).